Question by Jen: HELP. Gout: WHAT IS the homeostatic control mechanism that is imbalanced and why it is imbalanced?
For my paper, gout can be an example of homeostatic (human) imbalance. (I have most of the paper done but I have two parts I need help with.)

-1. For this condition, what is the homeostatic control mechanism that is imbalanced and why it is imbalanced?

-2. Is negative/positive feedback involved? If so, how?

Best answer:

Answer by ScottD
It’s usually caused by hyperuricemia. This is an increase in the production of uric acid in the blood. So, you need to look at some of the causes of that to see why it’s imbalanced (i.e. what homeostatic control is off). Hypertension could be a common cause of this. Diabetes and renal insufficiency could be another potential cause.

These could be caused by lifestyle or genetics.

I’m pretty sure this would be considered positive feedback because it is similar or like an inflammatory response because gout can be presented as red, hot, and swollen. In positive feedback systems, something is usually amplified.

Know better? Leave your own answer in the comments!

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